I was skimming through Blood! last night, and I'm not entirely sure how close it is. I think a conversion wouldn't be too difficult--not that you would have to, as everything you can do in this game you can probably do in BRP. I really only mentioned it because of the damage tables.
The system boils down to everything being a percentage, keeping it a very "human level" game. Both attributes and skills are percentages. Attributes don't come into play unless there isn't a skill to cover the thing your PC is doing--or an attribute is being directly acted upon (both like BRP). There are also derived attributes (Health, Sanity, etc.) from the main attributes. You also need the varied dice for Blood! that BRP also needs. But there isn't a resistance table. Mostly, Blood! is about setting (or is it theme?)--mainly 80's style gory, slasher horror whether you want supernatural elements or not. But I really like the write ups of the monsters--really horrific stuff. The author also took all the Ann Rice and WoD romanticized fluff out of vampires to make them into true horror creatures. Funnily enough, the company that makes Blood! also has a D20 rpg making fun of people who read Ann Rice books and Play WoD.
Oh yeah, I forgot, they have a RuneQuest conversion ebook. I think that pretty much answers everything.
RPGNow.com - Postmortem Studios - BloodQuest