Go for it!
Many of the MRQ authors (like Lawrence Whitaker) know BRP very well and the systems are very interchangeable.
I liked MRQ RuneMagic, and having looked at RQ Slaine I like the EarthPower magic.
In reverse if you like MRQ and yet want to use the magic systems from the Unknown East for Elric, go for it.
As for hit locations, well they are in the BRP rulebook (as an option I think) so then you could simply use the BRP hit locations, or even port the MRQ version over into your new mix and match game.
Personally I'd try and do it the other way (I've grow out of hit locations).
I know that any BRP games I run personally will probably be a mix and match between MRQ and BRP.. it's great tha there is so much d100 based gaming stuff out there.. even if it may have stolen Chaosium's thunder.
Worth noting is that this summer an OGL game will come out called SimpleQuest which may well be a simpler and refined system to hang your gaming off, whilst staying within the fold of the d100 trope.
SQ is from Newt Newport and will be 100% OGL.
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