Cthulhu Now (at least the German edition, I do not know the English one) has many modern
professions and the related modern skills. As for cultures, I think this would mostly be a mat-
ter of "fluff" instead of game mechanics. I am working with colleagues from Ghana, Korea and
Russia, and while they are certainly different from my German colleagues, I could not model
these differences in game mechanics without creating silly stereotypes, I could only express
them in the narrative material.
"Mind like parachute, function only when open."
(Charlie Chan)