After seeing the two episodes of Tabletop, where Dragon Age pen and paper RPG creator Chris Pramas ran a game for Wil Wheaton and friends, I immediately thought it would've been so much cooler had it been one of The Design Mechanism people running a game of RuneQuest. The videos can be watched on Youtube: Part One and Part Two.
Tabletop might not be willing to do an episode on another RPG, since because of the confines of the format the result would look pretty similar despite the differences in the game system, the adventure and the GM. I think, however, that a video like this, if done well, would be excellent promotion for a less known roleplaying game such as RuneQuest.
Now I understand that The Desing Mechanism being essentially a two man shop with a lot of work in their hands might not be able to divert the resources for a professional quality video like this, useful though it might be. But since they will eventually be running games at conventions it would be great to have perhaps some of their fans to record and edit a session of Loz or Pete running e.g. the RQ GM Pack adventures.
Of course a professionally produced video like the ones at Tabletop would be so much better, so if there is any chance of that kind of thing happening I would love to see it.